Endocrine Abstracts

Pseudoacromegaly is associated with acromegalic phenotype but normal insulin like growth factor-1 (IGF-1) levels and suppressed growth hormone levels. The reasons of this condition may be pachydermoperiostitis insulin resistance, drug intake such as minoxidil and hypothyroidism (4). We describe pachydermoperiostitis in a patient with hyperthyroidism and non-secretory pituitary macroadenomas.Clinical case: A 62 year old man presented with palpitation, swe...

Prolactinoma is the most common cause of chronic hyperprolactinemi and drugs that rise serum prolactin levels have been ruled out. Altough almost all of them arise within the sella turcica, there are some rare cases in which prolactinoma is located outside the intrasellar region, so it is defined as ectopic prolactinoma. Neuroleptics (e.g., haloperidol, chlorpromazine, risperidone.) can elevate serum PRL to levels that usually are detected with prolactinomas. We report a case ...

A 21-year-old female (height: 148 cm, weight: 38 kg, and BMI: 17) was referred to our endocrinology outpatient polyclinic with the complaints of severe abdominal pain and severe hypertriglyceridemia. The patient’s medical history revealed diabetes and FMF. Physical examination revealed a marked loss of subcutaneous fat from the extremities leading to prominence of muscular contours and veins, with excess fat around the face, submental and dorsocervical region. Despite the...

Pituitary apoplexy (PA) is an endocrine emergency characterized by acute, severe headache, visual disturbances, ophthalmoplegia, hypopituitarism and altered consciousness. This condition usually arises in an underlying pituitary adenoma. 27-year-old female without a known pitutary lesion presented to the emergency department in December 2015 with a 8-hour history of with sudden and severe frontal headache, fever, blurred vision, nausea, confusion at 36 weeks of gestation. The ...

Aspergillosis is a major problem in immunosupressed patients. We report a 65-year-old male patient with chronic renal failure (CRF) due to diabetic nephropathy who had arthralgy, malaise and high C-reactive protein level. Chest computed tomography revealed that thyroid nodule in the left thyroid lobe. Fine-needle aspiration biopsy of the thyroid revelead thyroidal invasion of Aspergillus. High-resolution computed tomograghy (HRCT) of the chest showed no evidence of intrapulmon...

Introduction: Recent study showed that patients with acromegaly have typical skin findings including increased sebum secretion, decreased transepidermal water loss, more alkaline, and colder skin surface correlated with serum GH and IGF1 levels.The aim of this study was to demonstrate the effect of functional skin changes on the skin flora in patients with acromegaly.Methods and designs: This case–control study was conducted i...

Introduction: Although dipeptidyl peptidase-4 (DPP-4) inhibitores are generally safe and are associated with less side effects compared to other oral antidiabetic medications, they could also be associated with some side effects including skin rash. Herein we report the first case of a type 2 diabetes patient who developed a painfull maculopapular rash induced by linagliptin, a widely used DPP-4 inhibitor.Case presentation: A-54-year old female patient w...

Purpose: The coronavirus disease 2019 (COVID-19) has a high morbidity and mortality in patients with chronic disorders. This study was aimed at assessing the frequency and outcomes of COVID-19 in patients with lipodystrophy syndrome and investigating the effect of restricted access to the hospital during pandemic on metabolic parameters.Methods: A survey comprising descriptive questions about the situation of the patients during the COVID-19 pandemic was...

Clinical Endocrinology, 2021, 94(6): 1043-1053 (DOI: https://doi.org/10.1111/cen.14426)...